Associations between Systemic Sclerosis and Thyroid Diseases

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Associations between Systemic Sclerosis and Thyroid Diseases

We have reviewed scientific literature about the association of systemic sclerosis (SSc) and thyroid disorders. A high incidence, and prevalence, of new cases of autoimmune thyroiditis (AT) and/or hypothyroidism have been shown in sclerodermic patients (overall in the female gender). An association among a Th1 immune-predominance, low vitamin D levels, and AT have been also shown in SSc patient...

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Association between atherosclerosis and parenchymal lung involvement in systemic sclerosis

Background: Systemic sclerosis is an autoimmune disease affecting connective tissues, (including epidermal, subepidermal, microvasculature, etc.), leading to various extent of end-organ damage. The leading cause of mortality among these patients is lung involvement. The cardiovascular events happen more frequently in patients suffering systemic scleroderma, comparing to healthy population. This...

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Associations between peripheral blood eosinophil counts in patients with systemic sclerosis and disease severity

Increased levels of serum pro-fibrotic cytokines have been reported in patients with systemic sclerosis (SSc). Some of these cytokines also play an important role in the differentiation and migration of eosinophils. The aim of this study was to determine whether eosinophilic inflammation is caused in SSc. We retrospectively reviewed the peripheral blood eosinophil counts in 70 untreated patient...

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Clinical characteristics and mortality in systemic sclerosis: a comparison between early- and late-referred diseases.

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ژورنال

عنوان ژورنال: Frontiers in Endocrinology

سال: 2017

ISSN: 1664-2392

DOI: 10.3389/fendo.2017.00266